Hebron's ancient Jewish cemetery was severely desecrated last week, Israel Radio reported. Police investigators said the cemetery has been targeted numerous times over the past year.
In the latest incident, a large number of tombstones were defaced, mezuzot were ripped off the local prayer house and other sacred items were damaged.
Hebron is Judaism's second holiest city, and is the biblical burial place of Abraham, Isaac and Jacob. It was also the first capital of King David.
In 1929, Arab Muslim riots ended the millennia-old Jewish presence in the city in an orgy of blood. Today, a small Jewish community of several hundred live among a largely hostile "Palestinian" population of several hundred thousand.